Share Success: Letters From Readers
I: From Becky
Submit Form on Thursday, August 28, 2008 at
my name is Becky and I am 54 and have had Osteoporosis
since 1998 (10 years). I am so excited that EZORB has
reversed my bone loss. I took two kinds of
bisphosphonates for 7 years. My bone density improved
slightly but my stomach irritation was so bad so I
quit taking it.
started taking EZORB Dec 05, I had a bone density test
after 6 months and saw a decline in the bone density.
I called the EZORB customer assistance and they told
me to take the product at least a year, so I stuck
with the EZORB waited 3 years for my next bone density
test and it was worth it. I am so excited! I went from
a -2.9 in my lumbar spine to a -2.5 and a -2.82 to a
-2.0 in my hip (so my hip went from osteoporosis to
have had osteoporosis since 1998 (10 years) spine was
2.2 then up to 2.9 now 2.5 hip was 3.23 now 2.0.
tell everyone that has bone density problems to try
this amazing product. It does work.
II: From Tamara
on Fri, 01 Aug 2008 07:17:51 -0600
My name is Tamara and I have lupus and fibromyalgia. I
was desperate, I tried everything to alleviate my
flares and painful periods. Nothing worked until I
tried EZorb. I have not even gone through one bottle
yet and as soon as I started taking it after a few
days I had so much energy and my flare ended.
will continue taking this. This is completely
III: From Wanda
Submit Form on Saturday, June 21, 2008 at 03:45:23
was in so much pain that I was about to give up
working and find a surgeon to take the bone spurs out
of my heels. Every step felt like blades were cutting
through the bottoms of my feet. Then I found EZorb
online and tried it.
about a month someone at work asked me why I was in
such a good mood. I suddenly noticed it was because I
was in less pain. I can't thank you enough can't wait
to see the results on the second bottle.
IV: From Dee
Submit Form on Fri, 20 Jun 2008 14:01:11 -0700
asked the Lord to lead me to something. I started
searching the internet. I got to where I could barely
couple of nights ago my husband and I took a two mile
walk. That's amazing. Before Ezorb, I could hardly get
to the bathroom at night.
have had pain for years. All at once the pain just
became so unbearable. The pain got into my ankle, up
into my lower leg. The Lord is so good he led me to
your website. Thank you so much. Ezorb seems to be
the Desk of EZorb Newsletter Editor:
newsletter is now read by over 50,000 subscribers
worldwide. Success stories you contribute will have
great impact on many people's life. Kindly email your
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As always your private information will never be
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Research News: Drugs to Build Bones May Weaken Them
Drugs: Fosamax, Actonel, Boniva and Reclast)
questions have emerged about whether long-term use of
bone-building drugs for osteoporosis may actually lead
to weaker bones in a small number of people who use
concern rises mainly from a series of case reports
showing a rare type of leg fracture that shears
straight across the upper thighbone after little or no
trauma. Fractures in this sturdy part of the bone
typically result from car accidents, or in the elderly
and frail. But the case reports show the unusual
fracture pattern in people who have used bone-building
drugs called bisphosphonates for five years or more.
patients have reported that after weeks or months of
unexplained aching, their thighbones simply snapped
while they were walking or standing.
of these women will tell you they thought the bone
broke before they hit the ground," said Dr. Dean
G. Lorich, associate director of orthopedic trauma
surgery at NewYork-Presbyterian/Weill Cornell and the
Hospital for Special Surgery. Dr. Lorich and his
colleagues published a study in The Journal of
Orthopaedic Trauma last month reporting on 20 patients
with the fracture. Nineteen had been using the bone
drug Fosamax for an average of 6.9 years.
year, The Journal of Bone and Joint Surgery published
a Singapore report of 13 women with low-trauma
fractures, including 9 who had been on long-term
doctors emphasize that the problem appears to be rare
for a class of drug that clearly prevents fractures
and has been life-saving for women with severe
osteoporosis. Every year, American adults suffer
300,000 hip fractures.
which makes Fosamax, says it will study whether the
unusual fracture pattern is really more common in
bone-drug users. Arthur Santora, Merck's executive
director for clinical research, noted that the
fracture accounted for only about 5 or 6 percent of
all broken hips, while drugs like Fosamax reduced the
risk for the other 95 percent.
fracture pattern did not emerge in placebo-controlled
studies of bone drugs. But those studies have lasted
only three to five years, although follow-up studies
of the drug users have lasted longer. Now that the
fracture pattern has been identified, researchers
expect more doctors to publish reports.
have several similar patients myself," said Dr.
Susan M. Ott, associate professor of medicine at the
University of Washington. "Prior to these recent
articles, there were a few cases here and a few cases
there, but they are kind of starting to add up."
are in a constant state of remodeling - dissolving
microscopic bits of old bone, a process called
resorption, and rebuilding new bone. After age 30 or
so, a woman's bones start to dissolve faster than they
can be rebuilt, and after menopause she may develop
thin, brittle bones that are easily broken.
Bisphosphonates, including Fosamax, Procter &
Gamble's Actonel and GlaxoSmithKline's Boniva, slow
some experts are concerned that microscopic bone
cracks that result from normal wear and tear are not
repaired when the bone remodeling process is
suppressed. A 2001 study of beagles taking high doses
of bisphosphonates found an accumulation of
microscopic damage, though there was no evidence that
their bones were weaker.
September, the medical journal Bone reported on a
study of 66 women, financed by Eli Lilly, that showed
an association between Fosamax use and an accumulation
of microdamage in bones.
January 2006, the medical journal Geriatrics published
an unusual autobiographical case report. Dr. Jennifer
Schneider, a 59-year-old physician from Tucson, wrote
that she was riding a New York City subway when the
train lurched. "I felt a crack and I fell,"
she recalled in an interview. "I knew I'd
fractured my femur."
Schneider, who had been taking Fosamax for seven
years, said she had had pain in her thigh, but X-rays
and scans had not found a problem.
recent years, another rare side effect has been
associated with bone drugs: osteonecrosis of the jaw,
in which a patient's jawbone rots and dies. Most
victims are cancer patients taking a potent
intravenous form of the drug, but a small number of
cases from ordinary users have been reported.
studies suggest there is little extra benefit in
taking the bone drugs more than five years. Dr. Lorich
says that doctors should monitor the bone metabolism
of long-term users and that some patients may want to
consider taking time off the drugs. When fractures do
occur, surgeons need to be alerted about long-term
drug use, because the fracture may require more
aggressive treatment and be slower to heal.
Ott says the focus should be on using bone drugs only
in patients with a fracture risk of at least 3 percent
over the next 10 years.
many of these people are not getting adequate
treatment that definitely is beneficial," Dr. Ott
said. "My major caution is that the
bisphosphonates should not be used in people who don't
have a high risk of fracture."
New York Times July 15, 2008
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